Best Bets for NCAA Basketball Picks Against the Spread for Tuesday, February 25

Published 2:22 am Tuesday, February 25, 2025

ATS Pick: Kent State -6.5 vs. Toledo

• Matchup: Toledo Rockets at Kent State Golden Flashes
• Time: 7 p.m. ET
• Date: February 25
• Computer Projection: Kent State by 10.3 points (Bet now on BetMGM)
• Spread: Kent State (-6.5)
• TV Channel: ESPN+
• Live Stream: Watch this game on ESPN+

ATS Pick: Santa Clara +6.5 vs. Gonzaga

• Matchup: Gonzaga Bulldogs at Santa Clara Broncos
• Time: 11 p.m. ET
• Date: February 25
• Computer Projection: Gonzaga by 3.0 points (Bet now on BetMGM)
• Spread: Gonzaga (-6.5)
• TV Channel: CBS Sports Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: Northwestern +2.5 vs. Minnesota

• Matchup: Northwestern Wildcats at Minnesota Golden Gophers
• Time: 7 p.m. ET
• Date: February 25
• Computer Projection: Northwestern by 0.8 points (Bet now on BetMGM)
• Spread: Minnesota (-2.5)
• TV Channel: Peacock

ATS Pick: Murray State -5.5 vs. Indiana State

• Matchup: Indiana State Sycamores at Murray State Racers
• Time: 8 p.m. ET
• Date: February 25
• Computer Projection: Murray State by 8.6 points (Bet now on BetMGM)
• Spread: Murray State (-5.5)
• TV Channel: ESPN+
• Live Stream: Watch this game on ESPN+

ATS Pick: Alabama -7.5 vs. Mississippi State

• Matchup: Mississippi State Bulldogs at Alabama Crimson Tide
• Time: 9 p.m. ET
• Date: February 25
• Computer Projection: Alabama by 10.2 points (Bet now on BetMGM)
• Spread: Alabama (-7.5)
• TV Channel: ESPN2
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Bet on this or any men’s college basketball matchup at BetMGM.

ATS Pick: Lindenwood +1.5 vs. Western Illinois

• Matchup: Lindenwood Lions at Western Illinois Leathernecks
• Time: 8:30 p.m. ET
• Date: February 25
• Computer Projection: Lindenwood by 1.0 points (Bet now on BetMGM)
• Spread: Western Illinois (-1.5)
• TV Channel: ESPN+
• Live Stream: Watch this game on ESPN+

ATS Pick: UL Monroe +12.5 vs. James Madison

• Matchup: James Madison Dukes at UL Monroe Warhawks
• Time: 7:30 p.m. ET
• Date: February 25
• Computer Projection: James Madison by 10.0 points (Bet now on BetMGM)
• Spread: James Madison (-12.5)
• TV Channel: ESPN+
• Live Stream: Watch this game on ESPN+

ATS Pick: Ohio -5.5 vs. Western Michigan

• Matchup: Ohio Bobcats at Western Michigan Broncos
• Time: 7 p.m. ET
• Date: February 25
• Computer Projection: Ohio by 7.8 points (Bet now on BetMGM)
• Spread: Ohio (-5.5)
• TV Channel: ESPN+
• Live Stream: Watch this game on ESPN+

ATS Pick: Miami (FL) +23.5 vs. Duke

• Matchup: Duke Blue Devils at Miami Hurricanes
• Time: 7 p.m. ET
• Date: February 25
• Computer Projection: Duke by 21.4 points (Bet now on BetMGM)
• Spread: Duke (-23.5)
• TV Channel: ESPN
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

ATS Pick: Colorado State -12.5 vs. Air Force

• Matchup: Colorado State Rams at Air Force Falcons
• Time: 9 p.m. ET
• Date: February 25
• Computer Projection: Colorado State by 14.6 points (Bet now on BetMGM)
• Spread: Colorado State (-12.5)
• TV Channel: MW Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)